Hi Joseph,
I don't know if you've seen it yet, but some new research has come out of University of Kent about overactive bladder, potentially linking its cause to bacterial infection.
The study found some OAB patients have "low-grade inflammation which is missed by conventional NHS testing" and that " in these patients the low-grade inflammation is associated with bacteria living inside the bladder wall". I know correlation doesn't equal cause but it's pretty interesting all the same.
Here is the link to their news article:
https://www.kent.ac.uk/news/science/10441/bacterial-infection-possible-cause-of-bladder-condition
And here is the link to the article:
http://ajprenal.physiology.org/content/early/2016/06/27/ajprenal.00339.2015
Altered urothelial ATP signalling in major subset of human overactive bladder patients with pyuria
Alberto Contreras-Sanz, Louise Krska, Aswini A Balachandran, Natasha L. Curtiss, Rajvinder Khasriya, Stephen Kelley, Matthew Strutt, Hardyal S Gill, Kevin M Taylor, Kylie J Mansfield, Changhao Wu, Claire M Peppiatt-Wildman, James Malone-Lee, Jonathan Duckett, Scott S. Wildman
American Journal of Physiology - Renal Physiology Jun 2016, ajprenal.00339.2015; DOI: 10.1152/ajprenal.00339.2015