I’ve been researching the similarities between h pylori infections, chronic and recurrent UTIs and IC/PBS, and there are many (primarily inflammation, chronic pain, localised white blood cells, epithelial damage/shedding, ulcers).
It’s estimated that anywhere between 30-50 percent of the world's population is infected with helicobacter pylori. Out of these infected people, a large proportion appears to remain asymptomatic, with a smaller percentage going on to develop significant gastrointestinal diseases (including transient or chronic gastritis, duodenal and gastric ulcers, gastric cancer and MALT lymphoma). What is it about the bacteria involved, or the host, that determines if a helicobacter pylori infection progresses into one of these related diseases? Is it to do with the bacteria's virulence factors? The host's immune system? A combination of both? Despite being infected and having chronic, active inflammation of the stomach lining, why do so many not experience symptoms?
Anyone??
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